Imperial Collage Healthcare

HLA-B*27 Typing (B27)

Clinical Indications
Although HLA B27 is present in approximately 10% of the normal population, it if found in 88-96% of patients with ankylosing spondylitis (AS). It is also associated with other rheumatological disorders, including Reiter's syndrome and is a strong diagnostic indicator for AS.  A positive result indicates the presence of this antigen.

Reference Range

Sample Required
5-10 mL Whole Blood

Sample Container
EDTA  ( 6 ml pink top)

Sample Volume
5 mls

Turnaround Time
14 days


Samples must be sent via first class post or courier

The laboratory is accredited for this test by the European Federation of Immunogenetics (EFI) however due to a change in platform it is currently awaiting UKAS accreditation under extension to scope.

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