The anti-PLA2R (IgG) antibody assay is a quantitative enzyme immunoassay (ELISA) for the in vitro measurement of IgG antibodies targeted against the M-type-phospholipase A2 receptor (PLA2R) on renal podocytes in patient sera.
The anti-PLA2R test is useful in the diagnosis and monitoring of primary membranous glomerulonephritis
Anti-PLA2R antibodies are positive in 75-80% of cases of primary membranous glomerulonephritis.
There is also evidence that levels of anti-PLA2R autoantibodies correlate well with disease activity and progression
Reference Range <14 RU/ml (negative)
Sample Required Serum - 5ml Gel SST (RUST TOP)
Samples should be transported at room temperature to the laboratory within 2-3 days from collection
Sample Volume Minimum 1ml Serum
Turnaround Time 14 days
This test is currently unaccredited due to a recent change in platform (manual to automation).