Test Background Neutrophils are an important component of the innate immune system and they are among the first cells to arrive at sites of injury. They play an important role in killing and removal of bacteria and fungi. This panel of tests is designed to assess neutrophil killing and phagocytosis. Tests offered as part of this panel are neutrophil burst (NBT), neutrophil phagocytosis and measurement of adhesion molecules (integrins CD18, CD11 and selectin CD62L) on the surface of the neutrophil.
Clinical Indications Recurrent infections.
Reference Range See report
Sample Required 10-20 mL heparin (green top) for adults5-10 mL heparin (green top) for children Do not separate or refrigerate Test within 24 hours
Sample Volume See above
Turnaround Time 7 days
Test must be pre-arranged with Charing Cross Laboratory on ext. 10130. Not performed for HIV positive patients.
Samples must be accompanied with blood from a normal healthy control. Samples must be <24 hours old on receipt and can only be accepted Monday to Thursday. Please contact the lab to arrange.