Test Background Myositis-specific antibodies are tested by immunoblot. This includes EJ, OJ, SRP and Ro-52 antibodies in addition to Ku, Mi-2, Jo-1, PM-Scl, PL-7, PL-12 which are already mentioned. Myositis is an inflammatory disease of the skeletal muscles. Myositis may be hereditary or caused by infections, malfunctions of the immune system or by toxins. Polymyositis in an inflammatory disease of the skeletal muscles with perivascular lymphocytic infiltration. Its aetiology is unknown. In case of skin involvement the disease is known as dermatomyositis.
Clinical Indications Suspected myositis.
Reference Range Negative
Sample Required RST (rust top)
Sample Volume 5-10 mL (1 mL serum)
Turnaround Time 28 days
Notes The laboratory is not accredited for anti EJ antibodies