Imperial Collage Healthcare

Myositis antibodies


Test Background
Myositis-specific antibodies are tested by immunoblot. This includes  EJ, OJ, SRP and Ro-52 antibodies in addition to Ku, Mi-2, Jo-1, PM-Scl, PL-7, PL-12 which are already mentioned. Myositis is an inflammatory disease of the skeletal muscles. Myositis may be hereditary or caused by infections, malfunctions of the immune system or by toxins. Polymyositis in an inflammatory disease of the skeletal muscles with perivascular lymphocytic infiltration. Its aetiology is unknown. In case of skin involvement the disease is known as dermatomyositis.


Clinical Indications
Suspected myositis.


Reference Range
Negative


Sample Required
RST (rust top)


Sample Volume
5-10 mL (1 mL serum)


Turnaround Time
28 days


Notes
The laboratory is not accredited for anti EJ antibodies


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