Imperial Collage Healthcare

Gastric parietal cell antibodies

Test Background
Tested as part of LKS screen. GPC antibodies are seen in association with autoimmune gastritis and pernicious anaemia. All positive samples will be tested for presence of antibodies to intrinsic factor. Suggest also measure vitamin B12 levels.

Clinical Indications
Pernicious anaemia (PA) Atrophic gastritis Present in the early stages of PA, frequently diminishing with disease progression.

Reference Range

Sample Required
RST (rust top)

Sample Volume
5-10 mL (1 mL serum)

Turnaround Time
7 days

From March 2020 this test will be unaccredited

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