Imperial Collage Healthcare

Factor H and factor I

Test Background
Membranoproliferative glomerulonephritis type II (MPGNII) is associated with dysregulation of the alternative pathway of complement circulation. Factor H and factor I control the alternative pathway activation, and deficiencies of these may lead to MPGNII.

Clinical Indications
Suspected membranoproliferative glomerulonephritis type II (MPGNII).

Reference Range
Antigenically present

Sample Required
RST (rust top)

Sample Volume
5-10 mL (1 mL serum)

Turnaround Time
28 days

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