Imperial Collage Healthcare

Cyclic citrullinated peptide (CCP) antibodies

Test Background
CCP antibodies may be detected in healthy people long before they have clinical symptoms of rheumatoid arthritis (RA). In both early and established RA, the test for CCP antibodies is more specific than that for rheumatoid factor (RF). CCP antibodies predict the eventual development of undifferentiated arthritis into RA, and are also a marker of erosive joint disease in RA. In conjunction with RF, anti-CCP offers greatly increased specificity for RA.

Clinical Indications
Differential diagnosis of arthritis.

Reference Range
<5 AU/mL

Sample Required
SST (gold top)

Sample Volume
5-10 mL (1 mL serum)

Turnaround Time
14 days

The laboratory is currently unaccredited for this test due to a change in platform.

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