Imperial Collage Healthcare

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Test Background
The S-100 protein family of acidic calcium binding proteins consists of 17 monomers, each of which exhibits a unique pattern of tissue-specific expression. Two of the monomeric proteins, S-100A1 and S-100B, are found in high concentrations in the nervous system of vertebrates. These two monomers form either homo- or hetero-dimers; S-100B is present in high concentrations in glial and Schwann cells. Several studies have demonstrated the value of S-100 in the management of patients with malignant melanoma.

Clinical Indications
Management of patients with malignant melanoma.

Reference Range
<0.15 µg/L

Sample Required
Serum (Red top or SST (gold top)

Sample Volume
0.5 mL


Stable at 2-8oC for 24 hours. Please freeze pending dispatch for analysis.

Send to lab frozen.

Turnaround Time
10 days

Grossly haemolysed samples are unsuitable for this assay.

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