Imperial Collage Healthcare

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Test Background
Following ovulation the corpus luteum secretes progesterone which prepares and maintains the endometrium for pregnancy. Progesterone concentration >30 nmol/L at mid-luteal phase confirms ovulation and values >20 nmol/L in the luteal phase are highly suggestive of recent ovulation. Progesterone rises during pregnancy, is used to support pregnancy in donor egg cycles, and is occasionally used in diagnosis and monitoring of ectopic pregnancy and miscarriage.

Clinical Indications
Confirmation of ovulation Suspected miscarriage, suspected ectopic pregnancy Monitoring of progesterone replacement therapy in those undergoing fertility treatment

Reference Range
Female follicular: <5 nmol/L Female luteal: >20 nmol/L

Sample Required
Serum (red top) or SST (gold top)

Sample Volume
0.5 mL

Turnaround Time
1 day

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