Imperial Collage Healthcare

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Procollagen 3 (P3NP)

Test Background
The amino-terminal peptide of type 3 procollagen (P3NP) is formed during the synthesis of type 3 collagen. Serum P3NP is used as a marker for hepatic fibrosis in patients on long-term, low-dose methotrexate.

Clinical Indications
Monitoring of patients receiving low-dose methotrexate therapy.

Reference Range
See report

Sample Required
SST (gold top) or serum (red top)

Sample Volume
0.5 mL

Turnaround Time
Up to 2 weeks

Not currently performed in house; this is a referred test.

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