Imperial Collage Healthcare

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Test Background

Glucagon is a naturally occurring 29 amino acid hormone produced by the pancreatic islet α-cells. Glucagon is generally considered to be a counter-regulatory hormone to insulin. In the rare pancreatic neuroendocrine tumour (NET) called glucagonoma, glucagon is secreted in excess. Therefore, plasma glucagon measurements can be used in the biochemical diagnosis of glucagonomas. Glucagon is measured as part of the Gut Hormone profile.

Clinical Indications
Glucagonoma: hyperglycaemia refractory to insulin, skin lesions, diarrhoea and stomatitis Suspected neuroendocrine tumour

Reference Range
0-50 pmol/L

Sample Required
See Gut Hormones

Sample Volume
See Gut Hormones

Turnaround Time
3 weeks

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