Imperial Collage Healthcare

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Dehydroepiandrosterone sulphate (DHEAS)


Test Background
DHEAS is derived from the adrenal glands. Blood measurements of DHEAS are useful to detect excess adrenal activity as seen in DHEA-secreting adrenal tumours or incidences of hyperplasia including certain forms of CAH. Women with PCOS tend to have normal or mildly elevated levels of DHEAS.


Clinical Indications
DHEAS assay is indicated for the differential diagnosis of PCOS and CAH Presentation of unexplained hirsuitism Presentation of adrenal mass, ie. suspected adrenal tumour


Reference Range
<11 Years : 0 - 5 μmol/L 11-19 years : 0 - 12 μmol/L 20-40 years : 0.7-11.5 μmol/L 40-60 years : 0.8-6.9 μmol/L >60 years : 0.4-4.7 μmol/L


Sample Required
Serum (red top)


Sample Volume
0.5 mL


Transport/Storage

Stable at 2-8oC for 24 hours. Please freeze pending dispatch for analysis.

Send to lab frozen.


Turnaround Time
1 week


Notes
Grossly haemolysed samples are unsuitable for this assay.


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