Test Background Bilirubin is formed as a by-product of haemoglobin catabolism and its concentration in the blood correlates with the degree of red cell turnover and hepatic function. Elevated bilirubin concentrations are found in liver cirrhosis, hepatitis, some autoimmune conditions, defective clearance, eg. Crigler-Najjar syndrome, Gilbert’s and hepatic cholestasis, eg. due to gallstones.
Clinical Indications Diagnosis and monitoring of primary hepatic impairment or secondary to other causes Diagnosis of haemolytic anaemia