Imperial Collage Healthcare

Angiotensin converting enzyme (ACE)

Test Background
Increased amounts of ACE often correlate to the presence of granulomas secondary to sarcoidosis, an idiopathic condition that often affects the lungs but may also affect the eyes, skin, nerves, liver and heart. About 50-80 % of patients with active sarcoidosis will have elevated levels of ACE.

Clinical Indications
Presentation of granulomas, a chronic cough or SOB, red watery eyes and/or joint pain.

Reference Range

19 years+                                             20 – 70 U/L

Plus a range for less than 19y                 29 – 112 U/L

Sample Required
SST (gold top)

Sample Volume
0.5 mL

Turnaround Time
SST: 1 day

For CSF ACE analysis see CSF Angiotensin Converting Enzyme in the Specialist Protein Section.

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