Imperial Collage Healthcare

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Hepatitis B surface antigen, hepatitis B serology, HBV testing

Test Background
Detection of antibodies to hepatitis B surface antigen. Acute illness causes liver inflammation, vomiting and jaundice. Chronic hepatitis B may eventually cause cirrhosis and liver cancer. The infection is preventable by vaccination.

Clinical Indications
Acute jaundice, history of IVDU or other risk behaviour.

Sample Required
RST (rust top)

Sample Volume
5 mL

Turnaround Time
3 days (Confirmation: non-negatives up to 10 days)


If  hepatitis B surface antigen (HBsAg) is positive, further tests for markers of infection HBe-antigen, HBe-antibodies and HB core IgM will be performed. Hepatitis B surface antigen (HBsAg) is included in the routine antenatal screen.

The Hepatitis B Surface Antigen assay is currently unaccredited due to a change in platform.

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