Hepatitis B surface antigen, hepatitis B serology, HBV testing
Test Background Detection of antibodies to hepatitis B surface antigen. Acute illness causes liver inflammation, vomiting and jaundice. Chronic hepatitis B may eventually cause cirrhosis and liver cancer. The infection is preventable by vaccination.
Clinical Indications Acute jaundice, history of IVDU or other risk behaviour.
Sample Required RST (rust top)
Sample Volume 5 mL
Turnaround Time 3 days (Confirmation: non-negatives up to 10 days)
If hepatitis B surface antigen (HBsAg) is positive, further tests for markers of infection HBe-antigen, HBe-antibodies and HB core IgM will be performed. Hepatitis B surface antigen (HBsAg) is included in the routine antenatal screen.
The Hepatitis B Surface Antigen assay is currently unaccredited due to a change in platform.