Voltage gated potassium channel antibodies are seen in neuromyotonia.
NMDA-R, LGI1 , CASPR, AMPA1/2, GABAB antibodies.
Clinical Indications Presentation of muscle cramps, myotonia-like symptoms, excessive sweating, myokymia and fasciculations Diagnosis of Morvan’s syndrome (sleep disorders, memory loss and confusion)
Normal = 0 - 69 pmol/L
Equivocal = 70-130 pmol/L
Positive = >130 pmol/
Sample Required RST (rust top), Gel SST (yellow top), Can also be performed on CSF
Sample Volume 5-10 mL (2 mL serum)
Turnaround Time 28 days
Not currently performed in house; this test is referred to the University Hospital, Birmingham.