Test Background Insulinoma-associated antigen 2 (IA2) - detected in 50-70% of children and 30-50% adults with a newly apparent diabetes mellitus type 1, levels decline with increasing age.
In persons without diabetes, they have a high predictive value for the individual risk of type 1 diabetes. IA2 antibodies are most frequent in patients with HLA DR4/HLA DQ8 genotype.
Clinical Indications Suspected type 1 diabetes (T1D)
Reference Range The normal range for this assay is <10 IU/ml
Sample Required Serum sample
Sample Container Rust top whole blood tube
Sample Collection whole blood
Sample Volume 5-10 mL (1 mL serum)
Transport/Storage Transported at room temperature. Once serum has been extracted, sample is stored at 4-6oC
Turnaround Time 14 days
This is newly implemented and the laboratory is currently awaiting accreditation for this test.