Imperial Collage Healthcare

Heparin Induced Thrombocytopenia (HIT) Antibody Quantitation


Test Background
Quantitation of antibodies to the heparin:PF4 (platelet factor 4) complex is performed by chemiluminescent technique. Results greater than a validated cut-off value are suggestive of HIT though all results should be discussed with the haematology clinical team.


Clinical Indications
For investigation into Heparin Induced Thrombocytopenia (HIT)


Reference Range

Results >1.00 U/mL are highly suggestive of HIT.

For advice with interpretation please contact the lab or haematology clinical team


Sample Required
4.5 mL sodium citrate (pale blue top) adults 1.8 mL sodium citrate (pale blue top) paediatrics


Turnaround Time
4 hours


Notes

Sample requests must be accompanied by a ‘4T’ HIT clinical probability score (available on The Source or from Special Coagulation lab at Hammersmith Hospital).
All requests must be discussed with and approved by the haematology clinical team.
Please Note: Samples will be rejected if under/over-filled, clotted or haemolysed


Results >1.00 U/mL are highly suggestive of HIT.

For advice with interpretation please contact the lab or haematology clinical team

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