Decreased CSF glucose corresponds to impaired function of the choroid epithelium, as well as consumption by bacterial pathogens and leukocytes. Altered CSF glucose may reflect the sequelae of disease rather than the specific pathology (microbial invasion), and may also be seen in numerous other disease states, such as meningeal neoplasia, chemical meningitis and subarachnoid haemorrhage.
CSF glucose concentrations <50-66 % of serum values are suggestive of bacterial meningitis.
Greater than 4 weeks 1.8-4.7 mmol/L
CSF in fluoride oxalate (grey top)