Test Background If prolonged treatment with Tobramycin is anticipated, regular monitoring of pre-dose serum levels will be required.
Clinical Indications Take a blood sample immediately prior to the 2nd dose (if duration greater than 48 hours). Do not wait for the result – give second dose as planned. If the level comes back ≥1mg/L the 3rd dose should be adjusted.
Reference Range Pre-dose (trough) <1mg/l
Sample Required Serum SST rust top
Sample Volume 0.5ml
Tobramycin assays are now referred externally to Bristol Antimicrobial Reference laboratory. Sample referral and reporting of results is managed by the Infection & Immunity laboratory.