Imperial Collage Healthcare

Anti-Phospholipase A2 Receptor Antibody (anit-PLA2R)


Test Background

The anti-PLA2R (IgG) antibody assay is a quantitative enzyme immunoassay (ELISA) for the in vitro measurement of IgG antibodies targeted against the M-type-phospholipase A2 receptor (PLA2R) on renal podocytes in patient sera.


Clinical Indications

The anti-PLA2R test is useful in the diagnosis and monitoring of primary membranous glomerulonephritis

Anti-PLA2R antibodies are positive in 75-80% of cases of primary membranous glomerulonephritis.

There is also evidence that levels of anti-PLA2R autoantibodies correlate well with disease activity and progression


Reference Range

<14 RU/ml (negative)


Sample Required
Serum - 5ml Gel SST (RUST TOP)


Sample Collection

Samples should be transported at room temperature to the laboratory within 2-3 days from collection


Sample Volume
Minimum 1ml Serum


Transport/Storage

Room temperature


Turnaround Time
14 days


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