Imperial Collage Healthcare

Beta-2 Transferrin (Asialo Transferrin, CDT)


Test Background
An asialo form of transferrin is produced in the cerebral parenchyma by lysosomal hydrolysis of the plasma derived protein from a sialic acid residue. Up to 30% of transferrin in lumbar CSF is in this asialo form.


Clinical Indications

  • ?CSF or Fluid.

  • If a fluid sample is suspected of being CSF, e.g. in possible CSF rhinorrhea, confirmation can be obtained by demonstrating the presence of the asialo band by electrophoresis and immunofixation.


Reference Range

N/A


Sample Required
Fresh fluid sample with an accompanying serum sample


Sample Volume
50µl Fluid


Turnaround Time

1 Week


(Samples are run as soon as possible on receipt to the Protein Lab; usually the same or next working day)


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