Test Background An asialo form of transferrin is produced in the cerebral parenchyma by lysosomal hydrolysis of the plasma derived protein from a sialic acid residue. Up to 30% of transferrin in lumbar CSF is in this asialo form.
?CSF or Fluid.
If a fluid sample is suspected of being CSF, e.g. in possible CSF rhinorrhea, confirmation can be obtained by demonstrating the presence of the asialo band by electrophoresis and immunofixation.
Reference Range N/A
Sample Required Fresh fluid sample with an accompanying serum sample
Sample Volume 50µl Fluid
(Samples are run as soon as possible on receipt to the Protein Lab; usually the same or next working day)