Imperial Collage Healthcare

Jo-1 antibodies


Test Background
This test is only performed if the antinuclear antibody (ANA) screen is positive. The ENA screen includes antibodies to RNP, Sm, SS-A, SS-B, Scl-70 and Jo-1. If the ENA screen is positive then individual specificities will be checked and subsequently confirmed by immunoblot assay.
Jo-1 antibodies are detected in patients with myositis, especially in combination with pulmonary fibrosis.


Clinical Indications

  • Suspected autoimmune-mediated connective tissue disorders
  • Suspected myositis


Reference Range

Negative
Positive range : 0-40 AU/mL


Sample Required
RST (rust top)


Sample Volume
5-10 mL (1 mL serum)


Turnaround Time
14 days


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