Antibodies against intrinsic factor are present in 50-60 % of patients with pernicious anaemia. Their presence may pre-date the development of B12 deficiency. It is recommended to also check vitamin B12 levels.
Differential diagnosis of pernicious anaemia (autoimmune causes are not refractory to dietary B12 supplementation).
RST (rust top)
5-10 mL (1 mL serum)