Test Background Insulin antibodies can be a cause of resistance to insulin and are highly specific.
Clinical Indications Differential diagnosis of type II diabetes mellitus (DM) and LADA (latent autoimmune diabetes in adults)
Screening of first degree relatives for risk of developing insulin-dependent DM (IDDM)
May also be used to determine the risk of IDDM in gestational diabetes
Reference Range Negative
Sample Required RST (rust top)
Sample Volume 5-10 mL (1 mL serum)
Turnaround Time 28 days
Notes Not currently performed in house; this test is referred to the Protein Reference Unit in Sheffield.