Imperial Collage Healthcare

Haemophilus antibodies


Test Background
IgG antibody levels to Haemophilus influenzae are requested as part of an immune deficiency screen for patients with recurrent or opportunistic infections. This test is only available for patients <4 years of age, and should be performed alongside pneumococcal and tetanus toxoid antibodies.
Only pneumococcal and tetanus toxoid antibodies should be tested in patients >4 years of age.


Clinical Indications

  • Assessment of an antibody response to haemophilus vaccine
  • Aiding the diagnosis of immunodeficiency (acquired, congenital or iatrogenic, ie. following administration of immunosuppressive agents)
  • Haemophilus influenza type b post-vaccination immune status in sickle-cell, immunocompromised or other select patients in whom recurrent episodes of pneumococcal/haemophilus infection have been observed


Reference Range

0.15 mg/L minimum protective level
1 mg/L optimum protective level


Sample Required
RST (rust top)


Sample Volume
5-10 mL (1 mL serum)


Turnaround Time
28 days


Notes
Not currently performed in house; this test is referred to the Department of Immunology, Dudley Road Hospital, Birmingham.

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