Imperial Collage Healthcare

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Factor V Leiden

Test Background
Factor V Leiden mutation causes hypercoagulability disorders. The blood develops a tendency to form abnormal blood clots that can block blood vessels. Patients with Factor V Leiden thrombophilia have a higher than average risk of developing DVT. The probability of developing a clot in a blood vessel depends on whether the patient inherits one or two copies of the Factor V Leiden mutation.

Clinical Indications
A significant proportion of patients who present with DVT or pulmonary embolisms have a Factor V Leiden mutation. It would be prudent to eliminate Factor V Leiden mutation as being the cause for any thrombotic event in any Caucasian patient below the age of 45, or in any person with a family history of venous thrombosis.

Sample Required
EDTA (lavender top)

Sample Volume
0.5 mL Please note, if the blood counts are abnormal (high or low white cell count), the volumes of blood should be adjusted accordingly.

Turnaround Time
10 working days

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