Imperial Collage Healthcare

Zinc


Test Background
Zinc is an essential trace element, stored mainly in muscle. Approximately 80 % of circulating zinc is present in the red cells. Zinc is a component of many enzymes, required for transcription factors, antioxidant function, immune system, respiration and neurological function, and is crucial for normal growth and maturation.


Clinical Indications
Suspected deficiency: symptoms include mouth ulcers, a characteristic rash, alopecia, abdominal pain and diarrhoea, with depression and lethargy; classically seen in a high phytate diet Rare inborn errors, eg. acrodermatitis entropathica Monitoring of nutritional requirements for patients receiving parenteral nutrition Hyperzincaemia syndromes


Reference Range

Serum/Plasma : 11-18 μmol/L Urine


Sample Required
Blood: Trace element free (royal blue top)Urine: 24 hour collection


Sample Volume
Blood: 1 mLUrine: 24 hour collection


Turnaround Time
2 weeks


Notes
Risk of zinc deficiency in elderly, alcoholic, critically ill patients, burns, excessive/prolonged gastrointestinal losses and high phytate diets.

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