Imperial Collage Healthcare

Urinary steroid profile


Test Background
Requested for investigations of suspected steroid hormone-secreting tumours, causes of virilisation, ie. enzyme deficiencies that cause a masculine appearance, or in cases of apparent electrolyte imbalance with or without hypertension.


Clinical Indications

  • Diagnosis of CAH (cliteromegaly/ambiguous genitalia of infants or delayed puberty/deranged electrolyte balance in late-onset CAH)
  • Diagnosis of adrenal hypofunction
  • Suspected aldosterone resistance/insensitivity
  • Diagnosis of adrenal tumours (common tumours secrete DHEAS, 11ß-hydroxyandrostenedione and pregnenolone)


Reference Range

See report


Sample Required
24 hour urine collection
Spot urine for babies/children


Sample Volume
24 hour urine collection
5 mL for babies/children


Turnaround Time
Up to 6 weeks


Notes
Not currently performed in house; this is a referred test.
Request should be made or sanctioned by a consultant endocrinologist.

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