Imperial Collage Healthcare

Sex hormone binding globulin (SHBG)


Test Background
SHBG is a protein that is produced by the liver and binds tightly to the hormones testosterone, dihydrotestosterone (DHT) and oestradiol, and transports them in the blood in an inactive form. Low concentrations in women may correspond with higher free testosterone concentrations leading to virilisation, while high levels in men (and conversely low free testosterone) is associated with impaired fertility, libido and erectile dysfunction.


Clinical Indications

  • Hirsuitism in women
  • Fertility, erectile dysfunction and/or reduced libido in men


Reference Range

Male : 15-55 nmol/L
Female : 30-100 nmol/L


Sample Required
Serum (red top)


Sample Volume
1 mL


Turnaround Time
1 week


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