Imperial Collage Healthcare

Protein (urine)


Test Background
Glomerular proteinuria results from increased transcapillary passage of proteins and is characterised by the loss of plasma proteins equal to or greater than albumin, eg. glomerular nephritis, nephritic syndromes and chronic kidney disease.
Tubular proteinuria results from a decrease in the capacity of the tubules to reabsorb protein and results in an increase in excretion of low molecular weight proteins, eg. Fanconi syndrome.
Overflow proteinuria occurs when increased serum concentrations of proteins of low molecular mass are filtered through the glomerulus and exceed the reabsorptive capacity of tubules, eg. Bence-Jones proteinuria, haemoglobinuria, myoglobinuria.


Clinical Indications

  • Diagnosis of nephrotic syndromes
  • Diagnosis and monitoring of pre-eclampsia
  • Monitoring of (early) chronic kidney disease
  • Monitoring myelomatous disease


Reference Range

Random : <20 mg/mmol creatinine
24 hour urine collection : <0.15 g/24 h


Sample Required
Random urine (preferred) or 24 hour urine collection


Sample Volume
Random urine: 1 mL
or 24 hour urine collection


Turnaround Time
Random urine: 1 day
24 hour urine: 2 days


Filter by A-Z

Select a test from the left to view more details.