Imperial Collage Healthcare

Phenobarbitone


Test Background
Phenobarbitone is a general central nervous system suppressant that has proven effective in the control of generalised and partial seizures. It is frequently co-administered with phenytoin for control of complex seizure disorders, and with valproic acid for complex partial seizures.


Clinical Indications

  • Therapeutic drug monitoring
  • Assessing compliance or toxicity (symptoms of overdosage include: ataxia, nystagmus, fatigue or attention loss, progressing to respiratory arrest when pulmonary support is not supplied manually)


Reference Range

10-40 mg/L


Sample Required
SST (gold top)


Sample Volume
0.5 mL


Turnaround Time
1 day


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