Imperial Collage Healthcare

Low density lipoprotein cholesterol (LDL)

Test Background
The fasting lipid profile assesses total cholesterol, total triglycerides and high density lipoprotein cholesterol. From these, low density lipoprotein cholesterol is calculated.

Clinical Indications
Family history of cardiovascular or other thrombotic events Diagnosis and monitoring of hyperlipidaemia Monitoring of high-risk groups, eg. hypertensive, obese, diabetics, etc.

Reference Range
<3.0 mmol/L

Sample Required
SST (gold top)

Sample Volume
0.5 mL

Turnaround Time
1 day


Non-HDL cholesterol (total chol minus HDL chol) is recommended for CVD risk prediction; fasting samples are not required for this.

Non-HDL cholesterol targets for patients treated for CVD risk reduction are 40 % reduction from baseline (NICE CG181, 2014) or <2.5 mmol/L (JBS3. Heart 2014;100:ii1)

The JBS3 CVD risk estimator is at

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