Clinical Biochemistry

Low density lipoprotein cholesterol (LDL)

Test Background
The fasting lipid profile assesses total cholesterol, total triglycerides and high density lipoprotein cholesterol. From these, low density lipoprotein cholesterol is calculated.

Clinical Indications
Family history of cardiovascular or other thrombotic events Diagnosis and monitoring of hyperlipidaemia Monitoring of high-risk groups, eg. hypertensive, obese, diabetics, etc.

Reference Range

Sample Required
SST (gold top)

Sample Volume
0.5 mL

Turnaround Time
1 day

Notes
GP comment
Chol: JBS Guideline treatment targets: HEART 2005:91 Sup.V
                                     High CVD risk goal    Minimum goal
Total Cholesterol                    <4.0                        <5.0
Non-HDL Cholesterol               <3.0                        <4.0
LDL-Chol (Calculated)             <2.0                        <3.0
See CVD risk prediction charts in BNF for primary prevention.
Please note LDL calculation is only valid if patient was fasting.
 
If Tg >4.5,
LDL Not valid when TG >4.5/Not Fasting. Use Non-HDL Cholesterol target.
 
Paediatric comments re Lipids
 
Total Cholesterol <4.4 mmol/L acceptable, >5.2 mmol/L high
LDL Cholesterol <2.8 mmol/L acceptable, >3.4 mmol/L high