Lp(a) is an independent risk factor for cardiovascular disease. Concentrations are genetically determined, with high concentrations being associated with the higher risk phenotype. Quantitation of Lp(a) is performed by an isoform insensitive immunoassay for improved accuracy
Measurement of Lp(a) should be considered in patients with a moderate or high risk of cardiovascular disease.
Cardiovascular Risk Stratification
Low Risk <75 nmol/L (<300 mg/L)
Borderline Risk 75 – 125 nmol/L (300 – 500 mg/L)
High Risk >125 nmol/L (>500 mg/L)
Serum preferred (red top), heparin (green top) and EDTA (lavender top) acceptable