Test Background Iron is present within the body in the porphyrin complex, haem and iron storage proteins. Excess iron is usually caused by hereditary haemochromatosis. Toxicity by poisoning is now less common, but may occur due to ingestion, eg. accidental ingestion of iron tablets or industrial exposure.
Clinical Indications Estimation of iron stores
Diagnosis of iron storage diseases
Measurement of urinary iron excretion during chelation therapy can help optimise the dosage
Reference Range <1 μmol/24 h
Sample Required Random urine or 24 hour urine collection
Sample Volume Random urine: 2 mL
or 24 hour urine
Turnaround Time 2 weeks
Notes Increased concentrations can be seen in haemochromatosis and proteinuria.