Imperial Collage Healthcare

Chromagranin B


Test Background

Chromagranins are raised in neuroendocrine tumours and can be used for monitoring and detecting recurrence. They are measured as part of the Gut Hormone profile.


Clinical Indications
Suspected gastrinoma/somatostatinoma or Zollinger-Ellison syndrome: hypergastrinaemia, dyspepsia, diarrhoea, steatorrhoea, mixed endocrinopathy VIPoma: watery diarrhoea, hypokalaemia, achlorhydria, hypotension and flushing/vasodilation Glucagonoma: hyperglycaemia refractory to insulin, skin lesions, diarrhoea and stomatitis


Reference Range

0-150 pmol/L


Sample Required
EDTA (lavender top) on ice rush to laboratory


Sample Volume
3mL of plasma


Turnaround Time
3 weeks


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