Test Background
Chromagranins are raised in neuroendocrine tumours and can be used for monitoring and detecting recurrence. They are measured as part of the Gut Hormone profile.
Clinical Indications Suspected gastrinoma/somatostatinoma or Zollinger-Ellison syndrome: hypergastrinaemia, dyspepsia, diarrhoea, steatorrhoea, mixed endocrinopathy VIPoma: watery diarrhoea, hypokalaemia, achlorhydria, hypotension and flushing/vasodilation Glucagonoma: hyperglycaemia refractory to insulin, skin lesions, diarrhoea and stomatitis
Reference Range 0-150 pmol/L
Sample Required EDTA (lavender top) on ice rush to laboratory
Sample Volume 3mL of plasma
Turnaround Time 3 weeks