Imperial Collage Healthcare

Chloride


Test Background
Serum chloride varies as a function of the body’s water and electrolyte homeostasis, in addition to being an index of acid-base. Chloride levels are largely regulated by the action of the kidneys and deranged amounts typically correlate with renal impairment.


Clinical Indications

  • Hyperchloraemia: indicates dehydration and is associated with hypernatraemia. Elevated levels also correspond to metabolic acidosis or respiratory alkalosis (through hyperventilation)
  • Hypochloraemia: typically associated with hyponatraemia but also occurs with prolonged vomiting or gastric suction, chronic diarrhoea, emphysema, COPD and metabolic alkalosis


Reference Range

Blood : 95-108 mmol/L
Urine : no reference interval


Sample Required
SST (gold top)
24 hour urine collection


Sample Volume
Blood: 0.5 mL
Urine: 24 hour collection


Turnaround Time
Blood: 1 day
Urine: 2 days


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