Imperial Collage Healthcare

Bilirubin (conjugated)


Test Background
Unconjugated bilirubin, arising from haem metabolism is carried in the blood bound to protein (primarily albumin). This bilirubin is freed from its protein binding in the liver where it is conjugated and excreted. Conjugation and excretion is usually an efficient process. The accumulation of conjugated bilirubin (also called direct) is always pathological.


Clinical Indications
Investigations of jaundice Differential diagnosis of cholestasis and cholecystitis


Reference Range

Over 1 month : 0-5 μmol/L Less than 1 month


Sample Required
SST (gold top) or heparin (green top)


Sample Volume
0.2 mL


Turnaround Time
1 day


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