Imperial Collage Healthcare

Beta-2-microglobulin (β2M)


Test Background
β2M is a component of the MHC class I molecule that is responsible for mediating antigen presentation to cytotoxic T cells and is ubiquitous to all cell types (with the exception of erythrocytes). Up-regulation of β2M is observed in haematological malignancy (principally MM) and may facilitate prognostic information as a function of deterioration in glomerular function.


Clinical Indications
Monitoring of established haematological malignancy


Reference Range

1.2-2.4 mg/L


Sample Required
SST (gold top)


Sample Volume
0.5 mL


Turnaround Time
1 week


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