Test Background BJP is a paraprotein immunoglobulin free kappa or lambda light chain produced by neoplastic plasma cells. Light chains can be immunoglobulin fragments or single homogenous immunoglobulins. They are found in urine as they are small and hence easily cleared by the kidneys.
Clinical Indications A full myelomatosis screen must include a urine sample for BJP as it is the only detectable paraprotein in approximately 20 % of all such cases
Reference Range Qualitative test (positive/negative)
Sample Required Random urine or 24 hour urine collection
Sample Volume Random urine: 5 mL
or 24 hour urine collection
Turnaround Time 1 week
Notes BJP will not be observed in non-secretory forms of multiple myeloma.