Imperial Collage Healthcare


Test Background
Trace elements can be essential or toxic. Trace element toxicity can occur as a result of occupational exposure, environmental exposure or iatrogenic toxicity. Any organ can be affected: the central nervous system, liver, kidneys, muscles or circulatory system. All elements can be toxic in excess. Those most commonly associated with toxicity include: aluminium, lead, arsenic, cadmium, mercury, thallium, barium, germanium, tellurium, tin, antimony, osmium, uranium.

Clinical Indications
Arsenic poisoning is generally caused by ingestion and can lead to the onset of gastrointestinal pain, vomiting, shock, diarrhoea, neuropathy and renal failure.
Ingestion of seafoods (fish, shellfish, seaweed) will cause an increase in blood and urine arsenic due to the presence of non-toxic organic forms of arsenic compounds. These foods should be excluded from the diet for several days before sampling.

Reference Range
Blood: <0.10 μmol/L Urine: <0.15 μmol/24 h

Sample Required
Blood: EDTA (lavender top) or heparin (green top)Urine: universal container for random sample or 24 hour collection

Sample Volume
Blood: 0.5 mLUrine: 0.5 mLor 24 hour urine collection

Turnaround Time
3 weeks

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