Imperial Collage Healthcare


Test Background
Amylase is produced in the pancreas to facilitate the digestion of starch; its (over)accumulation in the blood might reflect an obstruction in the pancreatic duct secondary to a gallstone or tumour, or may be due to the presence of acute/chronic pancreatitis.

Clinical Indications
Pancreatitis-like presentation: severe abdominal pain, fever, loss of appetite or nausea Suspected malignancy (pancreatic, salivary, prostate, lung and ovarian) Cholecystitis Post-operative assessment following intra-abdominal surgery or ERCP Urinary amylase may be used for monitoring treatment of acute pancreatitis while hyperamylasuria is diagnostic of late-presentation acute pancreatitis (when levels in serum have typically already declined) Increased blood amylase levels with normal or low urine amylase levels may indicate decreased kidney function or the presence of macroamylasaemia

Reference Range
Blood: 0-90 IU/L Urine: no reference range

Sample Required
SST (gold top) Urine: 24 hour collection

Sample Volume
Blood: 0.5 mL Urine: 24 hour collection

Turnaround Time
Blood: 1 day Urine: 2 days

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