Test Background Impaired metabolism of proteins secondary to a urea-cycle defect (inborn error of metabolism), severe liver disease, a reduction in vascular perfusion of the liver, renal failure and Reye’s syndrome all cause the accumulation of toxic levels of ammonia in the blood.
Clinical Indications Irritability, tiredness, seizures, respiratory failure, difficulty in breathing and vomiting in neonates/infants Presentation of hepatic encephalopathy-type symptoms
Sample Required Lithium Heparin (green top) on ice rush to laboratory
Sample Volume 0.5 mL
Turnaround Time Within 4 hours