Imperial Collage Healthcare

Alkaline phosphatase (ALP)


Test Background
ALP is typically ubiquitous but predominates in the liver, bile ducts, bone and intestinal tissues. Leakage into the vasculature correlates with increased ALP turnover secondary to organ/tissue damage or increased production as a consequence of growth cycles, pregnancy or metastasis.


Clinical Indications

  • Bone pain, suspected liver impairment
  • Differential diagnosis: liver vs. bone causes (see ALP isoenzymes) consider also GGT


Reference Range

Adult : 30-130 IU/L
Less than 1 year : 150-500 IU/L
1-5 years : 150-770 IU/L
6-10 years : 135-540 IU/L
Male 11-14 years : 90-550 IU/L
Female 11-14 years : 50-415 IU/L
Male 15-20 years : 60-370 IU/L
Female 15-20 years : 50-175 IU/L


Sample Required
SST (gold top)


Sample Volume
0.5 mL


Turnaround Time
1 day


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