Imperial Collage Healthcare

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Alkaline phosphatase (ALP)


Lab Code : ALP


Test Background
ALP is typically ubiquitous but predominates in the liver, bile ducts, bone and intestinal tissues. Leakage into the vasculature correlates with increased ALP turnover secondary to organ/tissue damage or increased production as a consequence of growth cycles, pregnancy or metastasis.


Clinical Indications
Bone pain, suspected liver impairment Differential diagnosis: liver vs. bone causes (see ALP isoenzymes) consider also GGT


Reference Range
Adult: 30-130 IU/L Less than 1 year: 150-500 IU/L 1-5 years: 150-770 IU/L 6-10 years: 135-540 IU/L Male 11-14 years: 90-550 IU/L Female 11-14 years: 50-415 IU/L Male 15-20 years: 60-370 IU/L Female 15-20 years: 50-175 IU/L


Sample Required
SST (gold top)


Sample Volume
0.5 mL


Turnaround Time
1 day


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