Lab Code : DOC
Test Background 11DOC and 11-deoxycorticosterone accumulate in the presence of a functional or cumulative 11β hydroxylase deficiency a cause of congenital adrenal hyperplasia (CAH). This is one of the less common presentations of CAH. Measured also in the overnight metyrapone test for assessment of hypoadrenalism.
Clinical Indications Clinical picture of CAH with any of the following: overnight metyrapone test, hypervolaemic hypernatraemia with or without hypertension or hypokalaemia
Reference Range See report
Sample Required Serum (red top)
Sample Volume 0.5 mL
Turnaround Time Up to 6 weeks
Notes 17α-hydroxyprogesterone should be measured first. Not currently performed in house; this is a referred test.