Test BackgroundThe fluorescent dye EMA (eosin-5-maleimide ) is used to label band 3 protein, which indirectly interacts with the spectrin-based cytoskeleton and membrane lipid bilayer in red blood cells.
Deficiency or abnormality of band 3 is seen in hereditary spherocytosis red cells, and has also been observed in cases of Southeast Asian ovalocytosis, congenital dyserythropoietic anaemia type II, and the cryohydrocytosis variants of stomatocytosis.
Sample Required 4 mL EDTA (lavender top) adults
0.5 mL EDTA (lavender top) paediatrics
Sample Volume 0.5 mL adult tube
0.2 mL paediatric tube
Turnaround Time Within 4 working days