Imperial Collage Healthcare

Rubella virus IgM antibodies by EIA

Test Background
Primary postnatal rubella virus infection is typically a mild self-limiting disease characterised by a maculopapular rash, fever, malaise and lymphadenopathy. In contrast to postnatal infections, primary prenatal infections may have devastating effects. In utero infections may severely damage the fetus, particularly if occurring during the first four months of gestation. The congenitally infected infant may exhibit one or more of a variety of defects, collectively known as the congenital rubella syndrome. Among these are low birth weight, cataracts, deafness, congenital heart disease and mental retardation. Both naturally-acquired and vaccine-induced immunity to rubella virus associated with antibody persistence have been shown to provide protection from clinical rubella upon re-infection.

Clinical Indications
Confirmation of current rubella infection. Please give detailed clinical information, including date of onset/contact with the suspected infection.

Reference Range
The presence of antibody levels of at least 10 IU/mL of sample is indicative of past exposure to rubella virus.

Sample Required
RST (rust top)

Sample Volume
5 mL

Turnaround Time
7 days

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