We are pleased to inform you that we are now offering prednisolone measurement by LC-MS/MS analysis.
Prednisolone is a commonly prescribed glucocorticoid; high doses are used in conditions such as Rheumatoid Arthritis and Polymyalgia Rheumatica for its anti-inflammatory actions. Low doses are used in conditions such as adrenal insufficiency and CAH for its corticosteroid replacement properties.
Serum prednisolone concentrations can be used to assess whether a dosing regimen provides suitable steroid replacement. To assess whether adequate steroid replacement is achieved on a prednisolone dosing regimen, a single prednisolone level should be taken 8 hours post dose.
Day curves may be of value in cases where there is difficulty in achieving an appropriate dosing regimen. Prednisolone should be administered at time point 0 and samples taken at 0, 1, 2, 4, 6 and 8 hours post dose.
We offer a full interpretative service for this assay.
Please contact Emma Walker if you have any queries about this service.
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